SICCC GERMS is the mnemonic that I use for the differential of vesicular rashes in children. Two major branch points are vaccinated vs. unvaccinated … THEN… febrile vs. afebrile 

  • SICCC
    • Smallpox
    • Impetigo
    • Chickenpox
    • Coxsackievirus (Hand, Foot, and Mouth Disease) 
    • Contact Dermatitis (Poison Ivy)
  • GERMS
    • Gladiatorum (HSV)
    • Eczema 
    • Rickettsialpox 
    • Molluscum Contagiosum 
    • Scabies
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