COPD
  Escherichia coli
  Klebsiella spp

Healthy, age <65 years, no recent antibiotic use —S. pneumoniae, H. influenzae, and Atypicals (mycoplasma, legionella, chlamydia)
     Amoxicillin – PO: 1 gram 3 times a day for 5 days
     Augmentin ER (Amox-Clav) PO: 2 grams every 12 hours for 5 days
     Cefpodoxime PO: 200 mg every 12 hours for 5 days
     Levofloxacin PO: 750 mg every 24 hours for 7 days

Azithromycin PO :500 mg on day 1, followed by 250 mg once daily for 4 days